Synthesis of Hydroxyapatite Nanostructure by HydrothermalCondition forBiomedical Application Synthesis of hydroxyapatite nanostructure
Iranian Journal of Pharmaceutical Sciences,
Vol. 5 No. 2 (2009),
1 April 2009
,
Page 89-94
https://doi.org/10.22037/ijps.v5.41191
Abstract
In this investigation, hydroxyapatite (HAp) nanostructure with uniform morphologies, controllable size, nano-dispersion and narrow-size distribution in diameter has been synthesized successfully by low-temperature hydrothermal process, and the as-synthesized powders were characterized by energy-dispersive X-ray spectroscopy, scanning electron microscopy, high-resolution transmission electron microscopy (HRTEM), Fourier transform infrared, and induced couple plasma (ICP). In the present work, a novel technique of sono-chemical of CaHPO4.2H2O/NaOH/distilled water with cetyltrimethylammonium bromide ((CH3(CH2)15N+(CH3)3Br-) designated as CTAB) under hydrothermal condition to synthesize HAp nanostructure was described. Furthermore, the usage of a high basic condition a water environment is the two crucial keys in ensuring the for mation of HAp the hydrothermal/sonochemical processes. However, the crystallite size andcrystallinity degree of the HAp increased with the addition of annealing temperature.Indeed, the present work will introduce new method in synthesis of HAs forscientific and medical engineering.
- Biocompatibility
- Hydrothermal condition
- Hydroxyapatite
- Nanocry-stalline
- Tissue engineering
How to Cite
References
[2]Suchanek W, Yoshimura M. Processing and properties of hydroxyapatite-based biomaterials for use as hard tissue replacement implants. J Mater Res 1998; 13: 94-117.
[3]Monma H. Catalytic behavior of calcium phosphates for decomposition of 2-propanol and ethanol.J Catal1982; 75: 200-3.
[4]Sugiyama S, Matsumoto H, Hayashi H, Moffat JB. Sorption and ion-exchange properties of barium hydroxyapatite with divalent cations.Colloid SurfaceA2000; 169: 17-26.
[5]Slater PR, Sansom JE, Tolchard JR. Development of apatite-type oxide ion conductors. Chem Rec 2004; 4: 373-84.
[6]Blasse G. The physics of new luminescent materials. Mater Chem Phys1987; 16: 201-34.
[7]Nakayama S, Sakamoto MJ. Electrical properties of new type high oxide ionic electrical properties of new type high oxide ionic conductor RE10Si6O27(RE=La, Pr, Nd, Sm, Gd, Dy). Eur Ceram Soc1998; 18: 1413-8.[8]Tao S, Irvine JTS. Preparation and characterisa-tion of apatite-type lanthanum silicates by sol-gelprocesses. Mater Res Bull2001; 36: 1245-58.
[9]Andres-Verges M, Fernandez-Gonzalez C,Martinez-Gallega M. Hydrothermal synthesis of calcium deficient hydroxyapatites with controlled size and homogeneous morphology. J Eur Ceram Soc1998; 18: 1245-50.
[10]Nagata F, Yokogawa Y, Toriyama M, Kawamoto Y, Suzuki T, Nishizawa K. Hydrothermal synthesis of hydroxyapatite crystals in the presence of methanol.J Ceram Soc Jpn1995; 103: 70-3.
[11]Kumar R, Prakash KH, Cheang P, Khor KA.Temperature driven morphological changes of chemically precipitated hydroxyapatite nanoparticles.Langmuir2004; 20: 5196-200.
[12]Elliott JC. Structure and chemistry of the apatites and other calcium orthophosphates. Amsterdam:Elsevier, 1994.
[13]Morgan H, Wilson RM, Elliott JC, Dowker SEP,Anderson P. Preparation and characterisation of monoclinic hydroxyapatite and its precipitated carbonate apatite intermediate. Biomaterials2000;21: 617-27.[14]Haverty D, Tofail SAM, Stanton KT, McMonagle JB. The structure and stability of hydroxyapatite. Phys Rev B2005; 71: 94103-9.
[15]Kay MI, Young RA. Crystal structure of hydroxyapatite.Nature1964; 204: 1050-2.
[16]Doi Y, Moriwaki Y, Aoba T, Takahashi J, Joshin K. ESR and IR studies of carbonate-containing hydroxyapatites. Calcif Tissue Int 1982; 34: 178-81.
[17]Reigner P, Lasaga AC, Berner RA, Han OH, Zilm KW. Mechanism of CO (Super 2-) 3 substitution in carbonate-fluorapatite; evidence from FTIR spectroscopy. Am Mineral1994; 79: 809-18.
[18]Elliot JC. The crystallographic structure of dental enamel and related apatites. Ph.D Thesis, London:University of London, 1964.
[19]Bonel GA. Contribution an l’etude de la carbonation Des apatites. Ann Chim1972; 7: 65-87.
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