Duodenal GIST mass with big management challenges
Researcher Bulletin of Medical Sciences,
Vol. 27 No. 1 (2022),
20 November 2022
,
Page e3
Abstract
Introduction: Gastrointestinal stromal tumor (GIST) is a rare mesenchymal tumor of the gastrointestinal (GI) tract that usually occurs in the stomach and the small intestine, respectively. This tumor often occurs in people over the age of 40 years, especially in the fifth and sixth decades of life. The range of symptoms varies from asymptomatic to symptomatic depending on the size and location of the tumor. The standard diagnostic of this tumor is the pathological examination of tissue specimens. Also today, the main treatment for this tumor is surgery and resection of the tumor.
Case Report: A 43-year-old woman presented with melena and a decrease in hemoglobin level to 4. The patient underwent upper and lower GI endoscopy, CT angiography, and EUS, which was reported a vascular lesion below the ampulla of vater. After laparotomy and Whipple procedure, pathology reported tumor as GIST. The patient was discharged from the hospital in good general condition.
Conclusion: we suggest that patients presented with gastrointestinal bleeding and the presence of a lesion in the diagnostic modalities, GIST should always be considered as a differential diagnosis.
- Gastrointestinal stromal tumor; GIST; Gastrointestinal bleeding
How to Cite
References
2. Choi H. Response evaluation of gastrointestinal stromal tumors. The oncologist. 2008;13:4-7.
3. Joensuu H, Vehtari A, Riihimäki J, Nishida T, Steigen SE, Brabec P, et al. Risk of recurrence of gastrointestinal stromal tumour after surgery: an analysis of pooled population-based cohorts. The lancet oncology. 2012;13(3):265-74.
4. Miettinen M, Lasota J. Gastrointestinal stromal tumors–definition, clinical, histological, immunohistochemical, and molecular genetic features and differential diagnosis. Virchows archiv. 2001;438(1):1-12.
5. Sornmayura P. Gastrointestinal stromal tumors (GISTs): a pathology view point. J Med Assoc Thai. 2009;92(1):124-35.
6. Khourgami Z, Mahmoudzadeh H, Khaheshi I, Bagheri M, Bagheri M, Aminian A. Gastrointestinal Stromal Tumors (Review of Literature). 2008.
7. Tada Y, Yamamoto M, Sawata S, Hara K, Sugesawa K, Ueshima C, et al. Ruptured Small Intestinal Stromal Tumor Causing Concurrent Gastrointestinal and IntraAbdominal Hemorrhage: A Case Report. Yonago acta medica. 2021;64(1):137-42.
8. Nishida T. Asian consensus guidelines for gastrointestinal stromal tumor: what is the same and what is different from global guidelines. Translational gastroenterology and hepatology. 2018;3.
9. Fletcher CD, Berman JJ, Corless C, Gorstein F, Lasota J, Longley BJ, et al. Diagnosis of gastrointestinal stromal tumors: a consensus approach. International journal of surgical pathology. 2002;10(2):81-9.
10. Greenson JK. Gastrointestinal stromal tumors and other mesenchymal lesions of the gut. Modern Pathology. 2003;16(4):366-75.
11. Miettinen M, Sobin LH, Sarlomo-Rikala M. Immunohistochemical spectrum of GISTs at different sites and their differential diagnosis with a reference to CD117 (KIT). Modern pathology. 2000;13(10):1134-42.
12. Tworek JA, Goldblum JR, Weiss SW, Greenson JK, Appelman HD. Stromal tumors of the abdominal colon: a clinicopathologic study of 20 cases. The American journal of surgical pathology. 1999;23(8):937.
13. DeMatteo RP, Lewis JJ, Leung D, Mudan SS, Woodruff JM, Brennan MF. Two hundred gastrointestinal stromal tumors: recurrence patterns and prognostic factors for survival. Annals of surgery. 2000;231(1):51.
14. Duffy JP, Hines OJ, Liu JH, Ko CY, Cortina G, Isacoff WH, et al. Improved survival for adenocarcinoma of the ampulla of Vater: fifty-five consecutive resections. Archives of Surgery. 2003;138(9):941-50.
15. Ryder NM, Ko CY, Hines OJ, Gloor B, Reber HA. Primary duodenal adenocarcinoma: a 40-year experience. Archives of surgery. 2000;135(9):1070-4. 16. Cameron JL, Riall TS, Coleman J, Belcher KA. One thousand consecutive pancreaticoduodenectomies. Annals of surgery. 2006;244(1):10.
- Abstract Viewed: 133 times